mediator of RNA polymerase II transcription subunit 7; hMED7; activator-recruited cofactor 34 kD component; ARC34; cofactor required for Sp1 transcriptional activation subunit 9; CRSP complex subunit 9; mediator complex subunit 7; RNA polymerase transcriptional regulation mediator subunit 7 homolog; transcriptional coactivator CRSP33 (MED7 ARC34 CRSP9)

Function: - component of the mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase 2- dependent genes. - constitutively sumoylated Structure: - belongs to the mediator complex subunit 7 family Compartment: nucleus

General

phosphoprotein transcription factor (TF)

Properties

SIZE: entity length = 233 aa MW = 27 kD COMPARTMENT: cell nucleus MOTIF: Ser phosphorylation site {S194}

Database Correlations

OMIM 605045 UniProt O43513 Pfam PF05983 Entrez Gene 9443 Kegg hsa:9443

References

UniProt :accession O43513