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mediator of RNA polymerase II transcription subunit 6; activator-recruited cofactor 33 kD component; ARC33; mediator complex subunit 6; hmed6; renal carcinoma antigen NY-REN-28 (MED6, ARC33)
Function:
- component of the mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase 2- dependent genes
- interacts with CTNNB1 & GLI3
Structure:
- belongs to the mediator complex subunit 6 family
Compartment: nucleus
General
transcription factor (TF)
Properties
SIZE: entity length = 246 aa
MW = 28 kD
COMPARTMENT: cell nucleus
Database Correlations
OMIM 602984
UniProt O75586
Pfam PF04934
Entrez Gene 10001
Kegg hsa:10001
References
UniProt :accession O75586
Component-of
mediator complex (mediator of RNA polymerase 2 transcription)