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actin-binding Rho-activating protein (striated muscle activator of Rho-dependent signaling, STARS, ABRA)

Function: - activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 & through a mechanism requiring Rho-actin signaling (putative) - binds actin (putative) Compartment: - localized to the I-band of the sarcomere & to a lesser extent to the sarcomeric structure between Z-lines (putative)

General

cytoskeletal protein

Properties

SIZE: MW = 43 kD entity length = 381 aa COMPARTMENT: cytoplasm MOTIF: actin interaction {240-285} actin interaction {352-381}

Database Correlations

UniProt Q8N0Z2

References

UniProt :accession Q8N0Z2