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Achaete-scute homolog 4 (Achaete-scute-like protein 4, ASCL4, HASH4)
Function:
- could be a transcriptional regulator involved in skin development
Structure: contains 1 basic helix-loop-helix (bHLH) domain
Compartment: nucleus (putative)
Expression:
- expressed in skin
- 7-fold higher expression in fetal skin than in adult skin
- weak expression also detected in fetal lung, aorta & brain, & in adult stomach, kidney, ovary & breast
General
nuclear protein
Properties
SIZE: entity length = 172 aa
MW = 19 kD
COMPARTMENT: cell nucleus
MOTIF: DNA-binding motif
SITE: 75-85
helix-loop-helix
NAME: helix-loop-helix
SITE: 86-125
FOR-BINDING-VIA: helix-loop-helix
Database Correlations
UniProt Q6XD76
Pfam PF00010
Kegg hsa:1215
References
UniProt :accession Q6XD76