achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1, ASCL3, HASH3, SGN1)

Function: - transcriptional repressor - inhibits myogenesis - efficient DNA binding requires dimerization with another bHLH protein Structure: contains 1 basic helix-loop-helix (bHLH) domain Compartment: nucleus Alternative splicing: named isoforms=1 Expression: - widely expressed in fetal & adult tissues

General

basic helix loop helix (bHLH) family transcription factor transcriptional silencer (transcriptional repressor)

Properties

SIZE: MW = 21 kD entity length = 180 aa COMPARTMENT: cell nucleus MOTIF: DNA-binding motif SITE: 95-105 helix-loop-helix NAME: helix-loop-helix SITE: 106-145 FOR-BINDING-VIA: helix-loop-helix

Database Correlations

UniProt Q9NQ33 Pfam PF00010

References

UniProt :accession Q9NQ33