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acetic acid/cortisol/propylene glycol otic (VoSol otic)

2% acetic acid in propylene glycol. Indications: - treatment of superficial bacterial infections of the external auditory canal Dosage: 1) insert saturated wick; keep moist for 24 hours 2) 5 drops TID/QID. 2%. 15 mL. VoSol HC adds 1% hydrocortisone. 10 mL. Adverse effects: 1) burning 2) irritation 3) uncommon (< 1%) a) systemic acidosis b) urologic pain c) hematuria Mechanism of action: antibacterial

General

acetic acid/cortisol/propylene glycol otic agent; otologic agent; ear preparation

References

  1. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
  2. Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998 - not on National VA formulary
  3. Kaiser Permanente Northern California Regional Drug Formulary, 1998