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absent in melanoma 1 protein (AIM1)
Function:
- suppressor of malignant melanoma (putative)
- interactions with cytoskeleton
Structure:
- belongs to the beta/gamma-crystallin family
- contains 12 beta/gamma crystallin 'Greek key' domains
- contains 1 ricin B-type lectin domain
General
cytoskeletal protein
Properties
SIZE: MW = 189 kD
entity length = 1723 aa
COMPARTMENT: cytoplasm
MOTIF: Beta/gamma crystallin 'Greek key' 1 {1022-1061}
Beta/gamma crystallin 'Greek key' 2 {1062-1117}
Beta/gamma crystallin 'Greek key' 3 {1123-1163}
Beta/gamma crystallin 'Greek key' 4 {1164-1206}
Beta/gamma crystallin 'Greek key' 5 {1218-1270}
Beta/gamma crystallin 'Greek key' 6 {1271-1313}
Beta/gamma crystallin 'Greek key' 7 {1319-1361}
Beta/gamma crystallin 'Greek key' 8 {1362-1404}
Beta/gamma crystallin 'Greek key' 9 {1415-1452}
Beta/gamma crystallin 'Greek key' 10 {1453-1496}
Beta/gamma crystallin 'Greek key' 11 {1502-1542}
Beta/gamma crystallin 'Greek key' 12 {1543-1584}
Ricin B-type lectin {1586-1719}
Database Correlations
OMIM 601797
UniProt Q9Y4K1
PFAM correlations
References
UniProt :accession Q9Y4K1