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ABI1/STX1A/SNAP25 complex
Structure:
- consists of ABI1, STX1A, SNAP25
General
molecular complex
Properties
COMPARTMENT: cell nucleus
SUBUNITS: Abl interactor 1
COMPARTMENT: cytoplasm
cell nucleus
MOTIF: acetylation site
SITE: N-TERMINUS
EFFECTOR-BOUND: acetyl
binding to WASF1 {18-79}
SNARE motif {45-107}
MOTIF: breakpoint {95-96}
Ser phosphorylation site {S183}
Tyr phosphorylation site {Y213}
Ser phosphorylation site {S216}
Ser phosphorylation site {S222}
Ser phosphorylation site {S225}
proline-rich region
SITE: 260-418
MOTIF: proline residue (SEVERAL)
Tyr phosphorylation site {Y333}
src homology 3 [SH3] domain
SITE: 446-505
MOTIF: Tyr phosphorylation site {Y455}
syntaxin-1A
COMPARTMENT: intracellular vesicle
MOTIF: Ser phosphorylation site {S14}
coiled coil {68-109}
SNARE motif {192-254}
transmembrane domain {266-286}
synaptosomal-associated protein 25
COMPARTMENT: intracellular vesicle
MOTIF: SNARE motif {19-81}
cysteine-rich region {85-92}
MOTIF: cysteine residue {C85}
MODIFICATION: palmitate
COMPARTMENT: membrane
cysteine residue {C88}
MODIFICATION: palmitate
COMPARTMENT: membrane
cysteine residue {C90}
MODIFICATION: palmitate
COMPARTMENT: membrane
cysteine residue {C92}
MODIFICATION: palmitate
COMPARTMENT: membrane
Thr phosphorylation site {T138}
SNARE motif {140-202}
MOTIF: peptide motif {180-181}
Ser phosphorylation site {S187}
References
UniProt :accession Q8IZP0
Components
Abl interactor 1; Abelson interactor 1; Abi-1; Abl-binding protein 4; AblBP4; eps8 SH3 domain-binding protein; eps8-binding protein; Nap1-binding protein; Nap1BP; spectrin SH3 domain-binding protein 1; e3B1 (ABI1, SSH3BP1)
synaptosomal-associated protein 25; SNAP-25; synaptosomal-associated 25 kD protein; super protein; SUP (SNAP25 SNAP)
syntaxin-1A; syntaxin-A; neuron-specific antigen HPC-1 (STX1A, STX1)