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80S termination complex


Interactions

molecular events

Related

protein synthesis termination

General

allosteric enzyme peptidyl transferase ribosome

Properties

SIZE: MW = 4200 kD COMPARTMENT: cytoplasm MOTIF: active site allosteric site P-SITE: transfer RNA MOTIF: anticodon loop AMINO-ACYL: protein A-SITE: eukaryotic release factor MOTIF: guanine nucleotide-binding site EFFECTOR-BOUND: guanosine triphosphate binding site EFFECTOR-BOUND: peptidyl transferase RNA-binding motif EFFECTOR-BOUND: termination codon

Components

40S ribosomal subunit 60S ribosomal subunit eukaryotic translation initiation factor 4E (eIF4E, mRNA cap-binding protein) messenger RNA transfer RNA (tRNA)