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6-phosphogluconolactonase (6PGL, PGLS)
Function:
1) hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate
2) carbohydrate degradation, pentose phosphate pathway
Structure:
- belongs to the glucosamine/galactosamine-6-phosphate isomerase family, 6-phosphogluconolactonase subfamily
Compartment: cytoplasm (putative)
Note:
- there is also a GDH/6PGL endoplasmic bifunctional protein that contains 6-phosphogluconolactonase activity
Related
GDH/6PGL endoplasmic bifunctional protein; endoplasmic bifunctional protein precursor [Includes: glucose 1-dehydrogenase, hexose-6-phosphate dehydrogenase, 6-phosphogluconolactonase] (6PGL, H6PD, G1DH)
General
hydrolase
Properties
SIZE: MW = 28 kD
entity length = 258 aa
MOTIF: active site
Database Correlations
OMIM 604951
UniProt O95336
Pfam PF01182
Entrez Gene 25796
KEGG correlations
ENZYME 3.1.1.31
References
UniProt :accession O95336