actin-like protein 6B; 53 kD BRG1-associated factor B; actin-related protein Baf53b; ArpNalpha; BRG1-associated factor 53B; BAF53B (ACTL6B, ACTL6, BAF53B)

Function: - component of the brain-specific chromatin remodeling complex (bBAF complex) - component of the neuron-specific chromatin remodeling complex (nBAF complex) - required for postmitotic neural development & dendritic outgrowth - ACTL6B is not essential for assembly of the nBAF complex but is required for targeting the complex & CREST to the promoter of genes essential for dendritic growth Structure: belongs to the actin family Compartment: nucleus

General

cytoskeletal protein nuclear protein

Properties

SIZE: entity length = 426 aa MW = 47 kD COMPARTMENT: cell nucleus MOTIF: domain {39-82}

Database Correlations

OMIM 612458 UniProt O94805 Pfam PF00022 Entrez Gene 51412 Kegg hsa:51412

References

UniProt :accession O94805