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45S rRNA gene

Codes for 45S ribosomal RNA which is processed to 28S, 5.8S, & 18S ribosomal RNA

Interactions

molecular events

General

ribosomal RNA gene (rRNA gene)

Properties

SIZE: entity length = 13000 NUCLEOTIDES MOTIF: rRNA upstream element SITE: -175 to -100 rRNA core promoter element SITE: -50 to 20 p53-response element transcriptional start site exon intron transcriptional termination site COPIES/HAPLOID-GENOME: 100

References

  1. Bell et al Science 241:1192 1988
  2. Watson et al Molecular Biology of the Gene, Benjamin Cummings, Menlo Park, CA 1987
  3. Farmer G, Bargonetti J, Zhu H, Friedman P, Prywes R, Prives C. Wild-type p53 activates transcription in vitro. Nature. 1992 Jul 2;358(6381):83-6. PMID: 1614538