1-(2-choloroethyl)-3-(2,5-dioxo-3-piperidyl)-1-nitrosourea (PCNU)

Presumptively an alkylating agent by analogy. Indications: brain tumors Pharmacokinetics: good penetration of the blood-brain barrier

General

alkylating agent nitrosourea antineoplastic agent (chemotherapeutic agent)

References

Levin et al, Neoplasms of the central nervous system, in: Cancer: Principles & Practice of Oncology, DeVita et al, eds, Lippincott, Williams & Wilkins, Philadelphia, 2001, pg 2119