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zinc finger protein 91 homolog (Zfp-91, ZFP91)
Function:
1) transcriptional regulation
2) cell proliferation and/or anti-apoptosis (putative)
Structure:
1) belongs to the krueppel C2H2-type zinc-finger protein family
2) contains 5 C2H2-type zinc fingers
Compartment: nucleus
Alternative splicing: named isoforms=2
Expression:
- expressed ubiquitously
- particularly high level in testis
- isoform 2 is testis specific
Pathology:
- overexpressed acute myelogenous leukemia (AML) most cases
General
other protein
Properties
SIZE: MW = 63 kD
entity length = 570 aa
COMPARTMENT: cell nucleus
MOTIF: alanine-rich region {21-67}
MOTIF: alanine residue (SEVERAL)
arginine-rich region {48-81}
MOTIF: arginine residue (SEVERAL)
Ser phosphorylation site {S103}
glutamate-rich region {197-282}
MOTIF: glutamate residue (SEVERAL)
Zn finger C2H2-type
SITE: 311-336
EFFECTOR-BOUND: Zn+2
Zn finger C2H2-type
SITE: 342-366
EFFECTOR-BOUND: Zn+2
Zn finger C2H2-type
SITE: 372-394
EFFECTOR-BOUND: Zn+2
Zn finger C2H2-type
SITE: 400-422
EFFECTOR-BOUND: Zn+2
Zn finger C2H2-type
SITE: 430-453
EFFECTOR-BOUND: Zn+2
Database Correlations
UniProt Q96JP5
Pfam PF00096
References
UniProt :accession Q96JP5