14-3-3 protein epsilon; 14-3-3E (YWHAE)

Function: - adapter protein implicated in regulation of both general & specialized signaling pathways - binds to many protein, usually by recognition of a phospho-Ser or phosphotThr motif - binding generally results in modulation of the activity of the binding partner - interacts with NDEL1, RGNEF & TIAM2 Structure: - homodimer - belongs to the 14-3-3 family Compartment: cytoplasm, melanosome

Properties

SIZE: entity length = 255 aa MW = 29 kD COMPARTMENT: cytoplasm MOTIF: acetylation site SITE: N-TERMINUS EFFECTOR-BOUND: acetyl Ser phosphorylation site {S210}

Database Correlations

OMIM 605066 UniProt P62258 Pfam PF00244 Kegg hsa:7531

References

UniProt :accession P62258