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WW domain-containing protein 1; kidney & brain protein; KIBRA; HBeAg-binding protein 3 (WWC1, KIAA0869)
Function: may interact with DDN
Structure: contains 2 WW domains
Compartment: cytoplasm
Alternative splicing: named isoforms=2
Expression:
- detected in brain, heart, colon & kidney
Note: UniProt uses WW domain-containing protein 1 as a synonym for Nedd-4-like E3 ubiquitin-protein ligase WWP1
General
phosphoprotein
Properties
SIZE: MW = 125 kD
entity length = 1113 aa
COMPARTMENT: cytoplasm
MOTIF: WW domain (W/rsp5/WWP domain) {6-39}
WW domain (W/rsp5/WWP domain) {53-86}
coiled coil {107-193}
serine-rich region {261-265}
MOTIF: serine residue (SEVERAL)
coiled coil {293-431}
glutamate-rich region {819-873}
MOTIF: glutamate residue (SEVERAL)
Ser phosphorylation site {S899}
coiled coil {1001-1032}
Database Correlations
UniProt Q8IX03
Pfam PF00397
References
UniProt :accession Q8IX03