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wnt3A proto-oncogene protein
Function:
- ligand for members of the frizzled family
- Wnt-3 & Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube
- interacts with PORCN (putative)
Structure: belongs to the Wnt family
Compartment:
- secreted, extracellular space, extracellular matrix
Expression:
- moderately expressed in placenta & at low levels in adult lung, spleen, & prostate
General
wnt proto-oncogene protein or int proto-oncogene protein
Properties
SIZE: entity length = 352 aa
MW = 39 kD
MOTIF: signal sequence {1-24}
cysteine residue {C77}
MODIFICATION: palmitate
COMPARTMENT: membrane
N-glycosylation site {N87}
N-glycosylation site {N298}
Database Correlations
OMIM 606359
UniProt P56704
Pfam PF00110
Entrez Gene 89780
Kegg hsa:8978
References
- Entrez Gene :accession 89780
- UniProt :accession P56704