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wnt10A proto-oncogene protein
Function:
- ligand for members of the frizzled family
- probable developmental protein
- may be a signaling molecule important in CNS development
- is likely to signal over only few cell diameters
Structure: belongs to the Wnt family
Compartment:
- secreted, extracellular space, extracellular matrix
Pathology:
- defects in WNT10A
- odontoonychodermal dysplasia
- Schopf-Schulz-Passarge syndrome
General
wnt proto-oncogene protein or int proto-oncogene protein
Properties
SIZE: entity length = 417 aa
MW = 46 kD
MOTIF: signal sequence {1-35}
N-glycosylation site {N106}
N-glycosylation site {N363}
Database Correlations
OMIM correlations
UniProt Q9GZT5
Pfam PF00110
Entrez Gene 80326
Kegg hsa:8032
References
- UniProt :accession Q9GZT5
- Entrez Gene :accession 80326