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WD repeat-containing protein 26; CUL4- & DDB1-associated WDR protein 2; myocardial ischemic preconditioning up-regulated protein 2 (WDR26, CDW2, MIP2, PRO0852)
Function:
- may be involved in MAPK pathways
- interacts with DDB1-CUL4A/B E3 ligase complexes
Structure:
- contains 1 CTLH domain
- contains 1 LisH domain
- contains 6 WD repeats
Compartment: cytoplasm
Alternative splicing: named isoforms=4
Expression:
- broadly expressed
- highest levels in heart & skeletal muscle
General
phosphoprotein
WD repeat protein family
Properties
SIZE: entity length = 661 aa
MW = 72 kD
COMPARTMENT: cytoplasm
MOTIF: Ser phosphorylation site {S121}
LisH {123-155}
CTLH {156-231}
WD repeat {353-392}
WD repeat {399-438}
WD repeat {444-484}
WD repeat {524-563}
WD repeat {566-608}
WD repeat {611-651}
Database Correlations
UniProt Q9H7D7
Pfam PF00400
Entrez Gene 80232
Kegg hsa:80232
References
UniProt :accession Q9H7D7