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WW domain-binding protein 2 (WBP-2, WBP2)
Function:
1) binds to the WW domain of YAP1, WWP1 & WWP2
2) interacts with NEDD4 via WW-binding 1 motif
Structure:
- contains 1 GRAM domain
Expression: ubiquitous
General
WW domain-binding protein
Properties
SIZE: MW = 28 kD
entity length = 261 aa
MOTIF: GRAM {1-84}
proline-rich region
SITE: 146-255
MOTIF: proline residue (SEVERAL)
WW-binding 1 {196-200}
Tyr phosphorylation site {Y232}
WW-binding 2 {248-252}
Database Correlations
OMIM 606962
UniProt Q969T9
Pfam PF02893
References
UniProt :accession Q969T9