vitamin K epoxide reductase complex (VKOR)

Function: 1) vitamin K metabolism 2) reduces inactive vitamin K 2,3-epoxide to active vitamin K Compartment: endoplasmic reticulum membrane Expression: - expressed in fetal & adult liver > fetal heart, kidney, & lung, adult heart & pancreas

General

multisubunit protein oxidoreductase

Properties

MOTIF: active site SUBUNITS: vitamin K epoxide reductase complex subunit 1 COMPARTMENT: endoplasmic reticulum MOTIF: exoplasmic domain {1-8} transmembrane domain {9-29} cytoplasmic loop {30-100} transmembrane domain {101-123} exoplasmic loop {124-126} transmembrane domain {127-149} MOTIF: cysteine residue {C132} MODIFICATION: cysteine residue {C135} cysteine residue {C135} MODIFICATION: cysteine residue {C132} cytoplasmic domain {150-163}

Database Correlations

UniProt Q9BQB6 Pfam PF07884 ENZYME 1.1.4.1

References

UniProt :accession Q9BQB6