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vitamin K epoxide reductase allele/allele (VKORC1 gene mutation)
Indications:
- assessment of sensitivity/resistance to warfarin
Clinical significance:
- tests for allelic variation in VKORC1
Related
vitamin K epoxide reductase complex subunit 1 (vitamin K1 2,3-epoxide reductase subunit 1, VKORC1, VKOR, MSTP134, MSTP576, UNQ308/PRO351)
warfarin sensitivity testing (CYP2C8, CYP2C9, CYP4F2, VKORC1)
General
genotyping (allele testing)
References
Prescriber's Letter 14(10): 2007
Genetic testing for warfarin
Detail-Document#: 231002
(subscription needed) http://www.prescribersletter.com