Search
vibegron (Gemtesa)
Indications:
- treatment of overactive bladder with symptoms of urge urinary incontinence, & urinary frequency in adults Contraindecations:
- not recommended for eGFR < 15 mL/min
Dosage:
- 75 mg PO QD
Tabs: 75 mg (Tablet may be crushed & mixed with applesauce)
Adverse effects:
- most common > 2%
- headache, urinary tract infection, nasopharyngitis, diarrhea, nausea, upper respiratory tract infection.
- warning: urinary retention [1]
Drug interactions:
- digoxin:
- measure serum digoxin concentrations before initiating GEMTESA
- monitor serum digoxin concentrations to titrate digoxin dose
Mechanism of action:
- beta-3 adrenergic agonist
Interactions
drug adverse effects of adrenergic receptor agonists
General
beta-3 adrenergic receptor agonist
Database Correlations
PUBCHEM cid=44472635
References
- HIGHLIGHTS OF PRESCRIBING INFORMATION
https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/213006s000lbl.pdf