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vesicle-associated membrane protein-associated protein A (VAMP-associated protein A, VAMP-A, VAP-A, 33 kD Vamp-associated protein, VAP-33, VAPA, VAP33)
Function:
1) vesicle trafficking
2) homodimer & heterodimer with VAPB
3) interacts with VAMP1, VAMP2, STX1A, BET1, SEC22C, OSBPL1A, OCLN
4) may associate with cytoskeleton
Compartment:
- cell membrane
- intracellular vesicles with SNARE proteins
- colocalizes with OCLN at the tight junction in polarized epithelial cells
Expression: ubiquitous
General
membrane protein
Properties
SIZE: MW = 27 kD
entity length = 242 aa
COMPARTMENT: cytoplasm
MOTIF: MSP {7-124}
coiled coil {161-200}
transmembrane domain {222-242}
Database Correlations
OMIM 605703
UniProt Q9P0L0
Pfam PF00635
References
UniProt :accession Q9P0L0