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venglustat; ibiglustat
Contraindications:
- treatment of GBA1-associated Parkinson's disease
Mechanism of action:
- brain-penetrant glucosylceramide synthase inhibitor
General
neurologic agent
Database Correlations
PUBCHEM correlations
References
- Giladi N et al.
Safety and efficacy of venglustat in GBA1-associated Parkinson's disease:
An international, multicentre, double-blind, randomised, placebo-controlled,
phase 2 trial.
Lancet Neurol 2023 Aug; 22:661.
PMID: 37479372
https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(23)00205-3/fulltext