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sucroferric oxyhydroxide (Velphoro)
Indications:
- hyperphosphatemia in patients on hemodialysis
Dosage:
- start: 500 mg PO TID with each meal
- tablets must be chewed not swallowed whole
- tablets may be crushed
- patients typically need 3 or 4 tablets/day
- maximum: 1000 mg TID
Tabs: 500 mg (chewable)
Adverse effects:
- diarrhea (6-24%)
- dicolored feces (12-16%)
- nausea
Drug interactions:
- coadministration of levothyroxine is contraindicated
- coadministration of vitamin D is contraindicated
- use caution with coadministation of alendronate or doxycycline
Notes:
- cost $855/month 2014
General
phosphate binder
References
- Medscape: sucroferric oxyhydroxide
http://reference.medscape.com/drug/velphoro-sucroferric-oxyhydroxide-999889
- Prescriber's Letter 21(4): 2014
Comparison of Phosphate Binders
Detail-Document#: 300413
(subscription needed) http://www.prescribersletter.com