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veliparib
Contraindications:
- adding veliparib to platinum-based chemotherapy for first-line treatment of current smokers with advanced squamous-cell lung carcinoma does not improve overall survival [1]
Mechanism of action:
- PARP1 & PARP2 inhibitor that enhances the activity of platinum-based chemotherapy in solid tumors
General
small inhibitory antineoplastic agent (ib drug)
References
- Reuters Staff
Upfront Add-On Veliparib May Not Help Smokers With Lung Cancer Live Longer.
Medscape. September 8, 2021
https://www.medscape.com/viewarticle/958125