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vascular endothelial growth factor [VEGF] receptor
Function:
- the VEGF-kinase ligand/receptor signaling system plays a role in vascular development & regulation of vascular permeability
Structure:
- VEGF receptors dimerize
Related
vascular endothelial growth factor (VEGF) inhibitor
vascular endothelial growth factor family protein (VEGF family)
Specific
vascular endothelial growth factor receptor 1; VEGFR-1; vascular permeability factor receptor; tyrosine-protein kinase receptor FLT; Flt-1; tyrosine-protein kinase FRT; Fms-like tyrosine kinase 1 (FLT1, FLT, FRT)
vascular endothelial growth factor receptor 2; VEGFR-2; kinase insert domain receptor; protein-tyrosine kinase receptor Flk-1; CD309 (KDR, FLK1)
vascular endothelial growth factor receptor 3; VEGFR-3; tyrosine-protein kinase receptor FLT4 (FLT4)
General
glycoprotein
tyrosine kinase receptor (RTK)
Properties
COMPARTMENT: plasma membrane
STATE: active state
MOTIF: ligand-binding site
FOR-BINDING-OF: vascular endothelial growth factor-A
glycosylation site
transmembrane domain
Tyr phosphorylation site
kinase domain
MOTIF: ATP-binding site
NAME: ATP-binding site
Database Correlations
ENZYME 2.7.10.1