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Usher syndrome type IIA

Epidemiology: 1) most common of form of Usher syndrome 2) most frequent cause of combined deafness & blindness in adults 3) affects 3-6% of children born with hearing impairment Genetics: - autosomal recessive disorder Clinical manifestations: 1) sensorineural hearing deficiencies at birth 2) later development of progressive retinitis pigmentosa 3) mild hearing impairment with normal vestibular responses

Database Correlations

OMIM 276901 Entrez Gene 7399

References

UniProt :accession Q9H6K4