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upper airway stimulation therapy; hypoglossal nerve-stimulating device (Inspire)
Indications:
- obstructive sleep apnea in patients who fail CPAP
Procedure:
- implanted neurostimulation device
- device is implanted in the upper chest,
- it senses breathing patterns, & mildly stimulates airway muscles, keeping the airway open
- device is turned on & off using a handheld remote control
Mechanism of action:
- stimulates hypoglossal nerve
Related
obstructive sleep apnea (OSA)
General
neurostimulation (nerve stimulation)
References
- Kelley KJ
FDA Approves Novel Implantable Device for Sleep Apnea.
NEJM Journal Watch. May 2, 2014
Massachusetts Medical Society
(subscription needed) http://www.jwatch.org
- Manufacturer's News Release. May 1, 2014
FDA Approves Inspire Upper Airway Stimulation (UAS) Therapy
for Obstructive Sleep Apnea.
http://www.multivu.com/mnr/7169651-fda-approves-inspire-upper-airway-stimulation-therapy-sleep-apnea
- Strollo PJ Jr1, Soose RJ, Maurer JT et al
Upper-airway stimulation for obstructive sleep apnea.
N Engl J Med. 2014 Jan 9;370(2):139-49
PMID: 24401051
- Malhotra A.
Hypoglossal-nerve stimulation for obstructive sleep apnea.
N Engl J Med. 2014 Jan 9;370(2):170-1
PMID: 24401056