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uncoupling protein
Function:
- mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis
- as a result, energy is dissipated in the form of heat
- may play a role in thermoregulation
Specific
mitochondrial brown fat uncoupling protein 1; UCP 1; thermogenin (UCP1, SLC25A7)
mitochondrial uncoupling protein 2; UCP 2; UCPH (UCP2 SLC25A8)
mitochondrial uncoupling protein 3; UCP 3 (UCP3 SLC25A9)
mitochondrial uncoupling protein 4; UCP 4; solute carrier family 25 member 27 (SLC25A27, UCP4, UNQ772/PRO1566)
General
carrier protein (transporter)
mitochondrial membrane protein
Properties
COMPARTMENT: mitochondrial membrane
MOTIF: membrane region
References
UniProt :accession O95847