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bilirubin unconjugated in serum (indirect bilirubin)

Reference values: - Adults: 0.0 - 1.1 mg/dL - Neonates: 0.6 - 10.5 mg/dL Clinical significance: - see bilirubin (conjugated/unconjugated) in serum - in a stress situation, erthropoiesis & unconjugated bilirubin can increase 10-fold - serum bilirubin will not exceed 4 mg/dL in patients with normal liver function - hemolysis can lead to very high unconjugated bilirubin in patients with even mild hepatic disease Increases: - hemolytic disorders - Gilbert's Syndrome - Crigler-Najjar Syndrome - neonatal jaundice - ineffective erythropoiesis - in the presence of drugs competing for glucuronide Principle: - see bilirubin (conjugated/unconjugated) in serum Preparation: - see bilirubin (conjugated/unconjugated) in serum Specimen: - see bilirubin (conjugated/unconjugated) in serum

Related

bilirubin (total) in serum/plasma (TBIL) bilirubin diglucuronide; conjugated bilirubin; direct bilirubin drugs that may affect liver function tests (LFTs)

General

bilirubin (conjugated/unconjugated) in serum bilirubin unconjugated in body fluid

References

  1. Kodak Ektachem 700 Analyzer Operator's Manual, Kodak Clinical Products, Rochester, New York.
  2. Kodak Ektachem Slide Package Inserts, Kodak Clinical Products Rochester, New York.
  3. Kodak Ektachem Training Manual, Kodak Clinical Products, Rochester, New York.