ubiquitin protein ligase activity (GO:0061630)

Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S --> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate. Note that this may include the extension of ubiquitin chains

Specific

APC-Cdc20 complex activity (GO:0090302) APC-fizzy related complex activity (GO:0090622) ubiquitin-ubiquitin ligase activity (GO:0034450)

General

ubiquitin-like protein ligase activity (GO:0061659) ubiquitin-protein transferase activity (GO:0004842)

References

gene ontology: GO:0061630