ubiquitin-conjugating enzyme E2 J1; non-canonical ubiquitin-conjugating enzyme 1; NCUBE-1; Yeast ubiquitin-conjugating enzyme UBC6 homolog E; HsUBC6e (UBE2J1, NCUBE1, CGI-76, HSPC153, HSPC205)

Function: - catalyzes the covalent attachment of ubiquitin to other proteins - seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum - protein modification; protein ubiquitination Structure: - belongs to the ubiquitin-conjugating enzyme family Compartment: - endoplasmic reticulum membrane - single-pass type IV membrane protein

General

membrane protein phosphoprotein ubiquitin-conjugating protein E2 (ubiquitin carrier protein)

Properties

SIZE: entity length = 318 aa MW = 35 kD COMPARTMENT: endoplasmic reticulum MOTIF: cysteine residue {C91} Ser phosphorylation site {S266} Ser phosphorylation site {S268} transmembrane domain {283-303}

Database Correlations

UniProt Q9Y385 Pfam PF00179 Entrez Gene 51465 Kegg hsa:51465 ENZYME 6.3.2.19

References

UniProt :accession Q9Y385