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ubiquitin-associated protein 2-like; protein NICE-4 (UBAP2L, KIAA0144, NICE4)
Function:
- phosphorylated upon DNA damage, probably by ATM or ATR
Structure:
- N-terminus is acetylated
- contains 1 UBA domain
- may be acetylated on Lys-976 & Lys-969
Alternative splicing: named isoforms=5
Expression: ubiquitous
Related
ubiquitin (UBCEP2, UBB, UBC)
ubiquitin-associated protein
ubiquitin-associated protein 2 (UBAP2 KIAA1491)
General
phosphoprotein
Properties
SIZE: entity length = 1087 aa
MW = 115 kD
MOTIF: acetylation site
SITE: N-TERMINUS
EFFECTOR-BOUND: acetyl
UBA domain {49-89}
Ser phosphorylation site {S360}
Ser phosphorylation site {S416}
Thr phosphorylation site {T419}
Ser phosphorylation site {S439}
Ser phosphorylation site {S453}
Ser phosphorylation site {S454}
Ser phosphorylation site {S458}
Ser phosphorylation site {S460}
Thr phosphorylation site {T461}
Ser phosphorylation site {S462}
Ser phosphorylation site {S467}
Ser phosphorylation site {S470}
Ser phosphorylation site {S471}
Ser phosphorylation site {S475}
Ser phosphorylation site {S476}
Ser phosphorylation site {S477}
Ser phosphorylation site {S604}
Ser phosphorylation site {S605}
Ser phosphorylation site {S607}
Ser phosphorylation site {S608}
Ser phosphorylation site {S609}
Tyr phosphorylation site {Y834}
Tyr phosphorylation site {Y835}
Thr phosphorylation site {T844}
Thr phosphorylation site {T847}
Ser phosphorylation site {S852}
Ser phosphorylation site {S859}
Database Correlations
UniProt Q14157
Pfam PF12478
Entrez Gene 9898
Kegg hsa:9898
References
UniProt :accession Q14157