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ubiquitin-conjugating enzyme E2 G2; ubiquitin carrier protein G2; ubiquitin-protein ligase G2 (UBE2G2)

Function: - accepts ubiquitin from the E1 complex & catalyzes its covalent attachment to other proteins - in vitro catalyzes Lys-48-linked polyubiquitination - involved in endoplasmic reticulum-associated degradation (ERAD) - protein modification; protein ubiquitination Structure: - belongs to the ubiquitin-conjugating enzyme family

General

ubiquitin-conjugating protein E2 (ubiquitin carrier protein)

Properties

SIZE: entity length = 165 aa MW = 19 kD MOTIF: active site MOTIF: cysteine residue cysteine residue {C89}

Database Correlations

OMIM 603124 UniProt P60604 Pfam PF00179 Entrez Gene 7327 Kegg hsa:7327 ENZYME 6.3.2.19

References

  1. UniProt :accession P60604
  2. OMIM :accession 603124