ubiquitin-conjugating enzyme E2 E2; UbcH8; ubiquitin carrier protein E2; ubiquitin-protein ligase E2 (UBE2E2, UBCH8)

Function: - accepts ubiquitin from the E1 complex & catalyzes its covalent attachment to other proteins - in vitro catalyzes Lys-11- & Lys-48-, as well as Lys-63-linked polyubiquitination - protein modification; protein ubiquitination Structure: - belongs to the ubiquitin-conjugating enzyme family

General

phosphoprotein ubiquitin-conjugating protein E2 (ubiquitin carrier protein)

Properties

SIZE: entity length = 201 aa MW = 22 kD MOTIF: Ser phosphorylation site {S19} cysteine residue {C139}

Database Correlations

OMIM 602163 UniProt Q96LR5 Pfam PF00179 Entrez Gene 7325 Kegg hsa:7325 ENZYME 6.3.2.19

References

UniProt :accession Q96LR5