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U6-snRNA
Only spliceosomal snRNA that lacks trimethyl guanosine cap. U6 snRNA is unique in that nucleotides are both added to & removed from its 3'-end U6-TUTase is responsible for a controlled elongation reaction results in the restoration of the four 3'-terminal UMP-residues found in newly transcribed U6 snRNA
General
small nuclear RNA (snRNA)
Properties
COMPARTMENT: cell nucleus
MOTIF: inverted GTP 5' cap structure
References
- Bindereif A, Wolff T, Green MR.
Discrete domains of human U6 snRNA required for the assembly
of U4/U6 snRNP and splicing complexes.
EMBO J. 1990 Jan;9(1):251-5.
PMID: 2136831
Component-of
7SK SNRNP complex