Tyrosine phosphorylation site

Tyrosine residue phosphorylated by tyrosine kinase. Phosphotyrosine has an elongated structure & apparently plays a crucial role in molecular recognition & the formation of protein/ protein complexes mediated largely, if not entirely, through SH2 (src homology-2) domains. The specificity tyrosine phosphate for SH2-domains is regulated by residues C-terminal to the phosphorylated tyrosine residue.

Related

src homology 2 [SH2] domain tyrosine kinase (protein tyrosine kinase, PTK)

General

phosphorylation site tyrosine residue (Tyr, Y)

References

Pawson FASEB J 8:1112 1994