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thromboxane A2
Produced by cyclooxygenase-1 in platelets. Causes platelet aggregation & vasoconstriction.
Interactions
molecular events
Related
arachidonate cyclooxygenase cascade
Thromboxane A2 receptor; TXA2-R; prostanoid TP receptor (TBXA2R)
General
arachidonate; arachidonic acid [C20:4w6, ARA]
thromboxane A
Properties
SIZE: MW = 304.5 G/MOL
COMPARTMENT: membrane
SECRETED-BY: platelet
MISC-INFO: 1/2life 1 MIN
Database Correlations
PUBCHEM correlations
References
- Textbook of Biochemistry with Clinical Correlations,
3rd ed., TM Devlin (ed), Wiley-Liss, NY 1992 pg 465
- Journal Watch 22(10):78, 2002
Cheng Y et al, Science 296:539, 2002
Vane JR, Science 296:474, 2002