tetraspanin-32 (pan-hematopoietic expression gene protein, tumor-suppressing subchromosomal transferable fragment cDNA 6, protein Phemx, TSPAN32, PHEMX, TSSC6)

Compartment: membrane Alternative splicing: named isoforms=5 Expression: - expressed ubiquitously at low levels - high levels of expression are confined to hematopoietic tissues including: peripheral blood leukocytes, thymus, spleen - expressed from early embryogenesis through to adulthood Note: - may be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay

General

anti-oncoprotein (tumor suppressor protein) tetraspanin (transmembrane-4-superprotein)

Properties

SIZE: MW = 35 kD entity length = 320 aa COMPARTMENT: cellular membrane MOTIF: transmembrane domain {14-34} transmembrane domain {60-80} transmembrane domain {90-110} transmembrane domain {203-223}

Database Correlations

OMIM 603853 UniProt Q96QS1 Pfam PF00335

References

UniProt :accession Q96QS1