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Trpc4-associated protein (short transient receptor potential channel 4-associated protein, Trp4-associated protein, TAP1 protein, TNF-receptor ubiquitous scaffolding/signaling protein, protein TRUSS, TRPC4AP, C20orf188, TRRP4AP)
Function:
1) role in activation of NFKB1 in response to ligation of TNFRSF1A
2) scaffolding protein to link TNFRSF1A to IKK signalosome
3) constitutively associated with TNFRSF1A
4) interacts with TRADD, TRAF2, CHUK, IKBKB & IKBKG
Alternative splicing: named isoforms=2
General
other protein
Properties
SIZE: MW = 91 kD
entity length = 797 aa
MOTIF: binding site
SITE: 1-400
FOR-BINDING-OF: TNF receptor-1A
Database Correlations
OMIM 608430
UniProt Q8TEL6
References
UniProt :accession Q8TEL6