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troponin-I

Function: - troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers Ca+2 sensitivity to striated muscle actomyosin ATPase activity - binds to actin & tropomyosin

Related

troponin-I in serum/plasma

Specific

troponin I, cardiac muscle; cardiac troponin I (TNNI3, TNNC1) troponin I, fast skeletal muscle; troponin I, fast-twitch isoform (TNNI2) troponin I, slow skeletal muscle; troponin I, slow-twitch isoform (TNNI1)

General

Ca+2 binding protein phosphoprotein protein subunit

Properties

MOTIF: Ca+2-binding site phosphorylation site actin-binding site FOR-BINDING-OF: F-actin

References

  1. Textbook of Biochemistry with Clinical Correlations, 3rd ed., TM Devlin (ed), Wiley-Liss, NY 1992 pg 961
  2. Stryer Biochemistry WH Freeman & Co, New York, 1988 pg 933

Component-of

troponin