tripartite motif-containing protein 69 (RING finger protein 36, RFP-like domain-containing protein trimless, TRIM69, RNF36, HSD34, HSD-34)

Function: - role in apoptosis (putative) - interacts with PML - phosphorylation is necessary for nuclear localization Structure: - belongs to the TRIM/RBCC family - contains 1 B30.2/SPRY domain - contains 1 RING-type zinc finger Compartment: nuclear speckle Alternative splicing: named isoforms=4

Properties

SIZE: MW = 57 kD entity length = 500 aa COMPARTMENT: cell nucleus MOTIF: nuclear translocation signal {1-152} MOTIF: RING-finger {41-82} EFFECTOR-BOUND: Zn+2 FOR-BINDING-OF: DNA motif coiled coil {161-255} B30.2/SPRY {305-500}

Database Correlations

UniProt Q86WT6 PFAM correlations

References

UniProt :accession Q86WT6