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transthyretin (prealbumin) in serum/plasma

Reference interval: - 20-36 mg/dL Clinical significance: - used as marker for nutritional assessment* - low levels associated with malnutrition - low levels also associated with inflammatory state - 1/2life is 48 hours, thus changes in serum levels respond faster to successful intervention than serum albumin (1/2life of 18-20 days) [4] - levels respond faster than serum albumin to nutrition reconstitution * not sufficiently sensitive or specific to determine adequacy of nutrient intake [4] Decreases: - malnutrition

Related

transthyretin; ATTR; prealbumin; TBPA (TTR PALB)

General

transthyretin (prealbumin) in body fluid

References

  1. Interpretation of Diagnostic tests, 8th edition, Wallach J, Lippincott, Williams & Wilkens, Philadelphia, 2007, pg 15
  2. Prealbumin Laboratory Test Directory ARUP: 50435
  3. Shenkin A Serum prealbumin: Is it a marker of nutritional status or of risk of malnutrition? Clin Chem. 2006 Dec;52(12):2177-9. PMID: 17138848
  4. Geriatric Review Syllabus, 8th edition (GRS8) Durso SC and Sullivan GN (eds) American Geriatrics Society, 2013 - Geriatric Review Syllabus, 9th edition (GRS9) Medinal-Walpole A, Pacala JT, Porter JF (eds) American Geriatrics Society, 2016

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enteral/parenteral nutrition management panel ovarian cancer 5 protein panel