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transient bullous dermolysis of the newborn (TBDN)
neonatal form of dystrophic epidermolysis bullosa
Pathology:
- diminished or abnormal anchoring fibrils at the dermal-epidermal junction
- electron-dense inclusions in keratinocytes
Genetics:
- associated with defects in COL7A1
Clinical manifestations:
- subepidermal blisters
- TBDN heals spontaneously or significantly improves within the first months & years of life
General
epidermolysis bullosa dystrophica (EBD)
Database Correlations
OMIM 131705
References
UniProt :accession Q02388