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tracheitis

Inflammation of the mucous membrane of the trachea. Etiology: 1) bacterial infection a) Staphylococcus aureus b) Haemophilus influenzae c) beta-hemolytic Streptococcus 2) viral infection a) influenza b) respiratory syntytial virus (RSV) c) parainfluenza d) many cases follow measles 3) relapsing polychondritis 4) Down's syndrome may be predisposing factor Epidemiology: 1) uncommon 2) most < 3 years of age 3) 75% of cases in winter Clinical manifestations: 1) croupy of brassy cough 2) inspiratory stridor 3) wheezing is unusual 4) fever (often > 102 F) 5) thick, purulent secretions a) poorly mobilized b) may become inspissated Laboratory: 1) complete blood count (CBC) (leukocytosis, left shift) 2) gram stain & culture of tracheal secretions 3) blood cultures are generally negative Special laboratory: - laryngoscopy (rule-out epiglottitis) Radiology: - lateral X-ray of neck (normal epiglottis) Complications: - outcome may be fatal Differential diagnosis: 1) viral croup 2) epiglottitis 3) diphtheria 4) herpes simplex (necrotizing) 5) cytomegalovirus (CMV) in immunosuppressed patients 6) invasive Aspergillosis in immunosuppressed patients Management: 1) airway maintenance a) suction b) endotracheal intubation as needed c) humidification of inspired gas 2) antibiotic therapy a) IV administration for 5-6 days b) oral therapy continued for total duration of 2 weeks c) levofloxacin or 3rd generation cephalosporin

Related

bronchitis laryngitis

Specific

croup (laryngotracheobronchitis)

General

tracheal disorder upper respiratory tract infection (URI, common cold)

References

  1. Stedman's Medical Dictionary 27th ed, Williams & Wilkins, Baltimore, 1999
  2. Ferri's Clinical Advisor, Instant Diagnosis and Treatment, Ferri FF (ed), Mosby, Philadelphia, 2003