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thiethylperazine (Torecan, Norzine, Toresten)

Tradenames: Torecan, Norzine. Indications: relief of nausea/vomiting Dosage: - 10 mg PO/IM/PR every 8 hours. Tabs: 10 mg. Injection: 5 mg/mL (2 mL) Adverse effects: 1) common (> 10%) - drowsiness, dizziness, dry mouth, dry nose 2) less common (1-10%) - agranulocytosis, cholestatic jaundice, confusion, convulsions, extrapyramidal effects, tachycardia, tardive dyskinesia, orthostatic hypotension, fever, headache, tinnitus Laboratory: - thiethylperazine in blood - thiethylperazine in serum/plasma - thiethylperazine in urine

General

anti-emetic

Properties

MISC-INFO: elimination route LIVER KIDNEY pregnancy-category - safety in lactation ?

Database Correlations

PUBCHEM correlations

References

  1. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
  2. Kaiser Permanente Northern California Regional Drug Formulary, 1998