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toceranib (Palladia)
Indications:
- treatment of canine mastocytoma
Mechanism of action:
- receptor tyrosine kinase inhibitor
Interactions
drug adverse effects of tyrosine kinase inhibitor(s)
General
small inhibitory antineoplastic agent (ib drug)
antineoplastic tyrosine kinase inhibitor
References
- Wikipedia: Toceranib
http://en.wikipedia.org/wiki/Toceranib
- London CA et al
Multi-center, placebo-controlled, double-blind, randomized
study of oral toceranib phosphate (SU11654), a receptor
tyrosine kinase inhibitor, for the treatment of dogs with
recurrent (either local or distant) mast cell tumor following
surgical excision.
Clin Cancer Res. 2009 Jun 1;15(11):3856-65. Epub 2009 May 26.
PMID: 19470739