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tissue polypeptide-specific Ag in serum/plasma
Clinical significance:
- useful marker of tumour activity in adult epithelial tumours [1]
- serum levels elevated in children with Wilms' tumor & neuroblastoma [1]
- levels elevated with liver disease (hepatoma, cirrhosis or chronic active hepatitis) [2]
- levels higher than 200 U/L suggest pancreatic cancer vs chronic pancreatitis [3]
General
tissue polypeptide-specific Ag in body fluid
References
- Rebhandl W, Rami B, Turnbull J et al
Diagnostic value of tissue polypeptide-specific antigen (TPS)
in neuroblastoma and Wilms' tumour.
Br J Cancer. 1998 Dec;78(11):1503-6.
PMID: 9836484 Free PMC Article
- Cetin T, Oguz A, Algan P, Yildirim IS.
The use of tissue polypeptide specific antigen as a marker in
liver diseases.
Turk J Gastroenterol. 2003 Sep;14(3):177-80.
PMID: 14655061 Free Article
- Slesak B, Harlozinska-Szmyrka A, Knast W et al
Tissue polypeptide specific antigen (TPS), a marker for
differentiation between pancreatic carcinoma and chronic
pancreatitis. A comparative study with CA 19-9.
Cancer. 2000 Jul 1;89(1):83-8.
PMID: 10897004